protein s deficiency การใช้

• Mutations in the PROS1 gene can lead to Protein S deficiency which is a rare blood disorder which can lead to an increased risk of thrombosis.
• Protein C and protein S deficiency have also been associated with an increased risk of skin necrosis on commencing anticoagulant treatment with warfarin or related drugs.
• Among researchers using the term, it has been described as a coagulation disorder that can present in conjunction with protein S deficiency and Factor V Leiden.
• There have also been cases in patients with other deficiency, including protein S deficiency, activated protein C resistance ( Factor V Leiden ) and antithrombin III deficiency.
• Examples of genetic tendencies include protein C deficiency, protein S deficiency, the Factor V Leiden mutation, hereditary anti-thrombin deficiency and prothrombin mutation G20210A . An important non-genetic risk factor is the use of estrogen-containing ( combined ) forms of hormonal contraception.